1st Edition

Polycystic Ovary Syndrome




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ISBN 9780824707460
Published April 3, 2002 by CRC Press
396 Pages

USD $190.00

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Book Description

Polycystic Ovary Syndrome discusses

  • the use of animal models in the study of PCOS
  • the occurrence of ovarian and adrenal abnormalities, cardiovascular risks, abnormal insulin secretion, and endothelial dysfunction in PCOS
  • modern therapeutic modalities, such as manipulation of diet and lifestyle, metabolic phenotyping, and treatment of hyperandrogenism
  • the effect of PCOS on long-term health
    Exploring the direct and indirect effects of PCOS in each stage of life, from puberty and adolescence to adulthood, Polycystic Ovary Syndrome is an in-depth and illuminating source for obstetricians and gynecologists; medical, reproductive, and pediatric endocrinologists; practitioners in family, internal, and pediatric medicine; epidemiologists; developmental biologists and toxicologists; and scientists and medical students in these disciplines.
  • Table of Contents

    Overview

    Historical Perspectives
    Joseph W. Goldzieher

    Epidemiology of Polycystic Ovary Syndrome

    Are Women with Polycystic Ovary Syndrome at Risk for Cardiovascular Disease?
    David S. Guzick and Evelyn O. Talbott

    Polycystic Ovary Syndrome and Long-Term Disease Risks
    Caren G. Solomon
    Premature Pubarche, Insulin Resistance, and Adolescent Polycystic Ovary
    Silva A. Arslanian and Selma Witchel

    Reproductive Abnormalities

    Morphological and Physiological Correlates of the Polycystic Ovary
    Gregory F. Erickson and Shunichi Shimasaki

    Ultrasound Examination of Polycystic and Multifollicular Ovaries
    Didier Dewailly, Robert Yann, Christophe Lions, and Yves Ardaens

    Adrenal Androgen Excess in Polycystic Ovary Syndrome
    Ricardo Azziz

    Neuroendocrine Dysfunction in Polycystic Ovary Syndrome
    John C. Marshall, Christine A. Eagleson, and Christopher R. McCartney

    Animal Models of Polycystic Ovary Syndrome

    A Transgenic Mouse Model of Functional Ovarian Hyperstimulation: Implications for Polycystic Ovary Syndrome
    Gabe E. Owens and John H. Nilson

    Prenatal Androgen Excess Programs for Polycystic Ovary Syndrome in Female Rhesus Monkeys
    David H. Abbott, Joel R. Eisner, Ricki J. Colman, Joseph W. Kemnitz, and Daniel A. Dumesic

    Metabolic Abnormalities and Their Relationship to Polycystic Ovary Syndrome

    Regulation of Metabolism and Reproduction Through the Insulin Receptor Substrat Protein Signaling System
    Deborah J. Burks and Morris F. White

    Molecular Mechanisms of Insulin Action in Polycystic Ovary Syndrome
    Andrea Dunaif

    Glucose Intolerance in Polycystic Ovary Syndrome: Role of the Beta Cell
    David A. Ehrmann

    Oligocentric Systems Associated with Central Obesity and Insulin Resistance: Models for Polycystic Ovary Syndrome
    John D. Brunzell

    Polycystic Ovary Syndrome and Coronary Vascular Disease: The Evidence?
    Robert A. Wild

    Vascular Function in Polycystic Ovary Syndrome
    Helmut O. Steinberg, Giancarlo Paradisi, Marguerite K. Shepard, and Alain D. Baron

    Genetics and Environmental Influences

    The Genetics of Polycystic Ovary Syndrome: A Model for the Analysis of Complex Genetic Diseases
    Margrit Urbanek, Deborah A. Driscoll, Jerome F. Strauss, III, Richard S. Spielman, Xinqi Wu, Andrea Dunaif, and Richard S. Legro

    Role of Genes Encoding Steroidogenic Enzymes in Polycystic Ovary Syndrome
    Stephen Franks, Neda Gharani, and Mark McCarthy

    The Role of Obesity in Polycystic Ovary Syndrome
    Ann E. Taylor

    Dyslipidemia in Polycystic Ovary Syndrome: Etiology and Response to Treatment
    Richard S. Legro

    Environmental Factors in Polycystic Overy Syndrome: Are There Plausible Cause-and-Effect Hypotheses?
    Claude L. Hughes, Ruchi Mathur, and David Geller

    Intervention/Prevention Strategies

    Lifestyle Factors and Polycystic Ovary Syndrome
    Robert J. Norman and Michael J. Davies

    Treatment of Hyperandrogenism
    Rogerio A. Lobo

    Ovulation Induction: Predictors of Ovarian Response and Clinical Outcomes
    Babek Imani, Marinus J. C. Eijkemans, J. Dik F. Habbema, Bart C. J. M. Fauser, and Egbert R. te Velde

    Diagnostic Criteria

    Polycystic Ovary Syndrome: Diagnostic Criteria
    R. Jeffrey Chang

    Index

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