1st Edition

Lung Growth and Development



ISBN 9780824797720
Published January 2, 1997 by CRC Press
768 Pages

USD $290.00

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Book Description

Reflects the explosion of information and technological breakthroughs that have facilitated investigations into the development of the lung-including recombinant DNA technology, molecular genetics, transgenics, and advances in lung cell and mo-lecular biology. Provides nearly 2800 bibliographic citations and over 170 tables, drawings, and x-rays to help clarify specific discussions.

Table of Contents

Structural Aspects of Prenatal and Postnatal Development and Growth of the Lung

Respiratory Epithelial Cell Gene Transcription

Role of Transcription Factors in the Development of the Pulmonary Epithelium

Epithelial-Mesenchymal Interactions in Lung Development

Differentiation of the Alveolar Epithelium in the Fetal Lung

Airway Gland Growth and Differentiation

Clara Cells

Growth and Differentiation of Tracheobronchial Epithelial Cells

Development of Innervation in the Lung

Development of Airway Smooth Muscle

Laminin in Lung Development

Collagens and Elastic Fiber Proteins in Lung Development

Cell-Cell and Cell-Matrix Interactions in Development of the Lung Vasculature

Neuropeptides and Lung Development

Developmental and Hormonal Regulation of the Surfactant System

Lung Injury When Development is Interrupted by Premature Birth

In Vitro Models of Lung Development and Cytodifferentiation

Hormonal Control of Compensatory Lung Growth

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Reviews

"
…McDonald is to be commended for producing a text that includes both in-depth coverage of major advances in lung development and an assessment of important research areas that remain unexplored.
"-The Physiologist